ArticleOxford medical case reports2026
Elongated inflamed uvula mimicking early recurrence on planning CT in post-laryngectomy laryngeal squamous cell carcinoma: a diagnostic pitfall in adjuvant radiotherapy.
Article in Oxford medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundLaryngeal squamous cell carcinoma (SCC) requires rigorous post-operative imaging surveillance to detect early recurrence, yet benign post-surgical changes may mimic malignancy and create diagnostic uncertainty. CASE PRESENTATION: We report a case of a 65-year-old male with well-differentiated laryngeal SCC who developed a suspicious lesion in the oropharynx on planning CT for adjuvant radiotherapy, 2 months after total laryngectomy, raising concern for early local recurrence. Clinical Discussion: Further assessment using multiplanar MRI demonstrated a well-defined elongated uvula with homogeneous enhancement, slightly hyperintense on T2 and without diffusion restriction, consistent with postoperative inflammatory change. Comparison with pre-treatment imaging confirmed its benign nature, preventing unnecessary biopsy or PET-CT.
conclusionThis case highlights the importance of distinguishing benign anatomical variants from malignant recurrence during post-operative surveillance imaging in head and neck oncology.
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