Evidence map›Paper›PMID 42186278›Full record

ReviewNutrition reviews2026

Spices for Targeting the Gut Microbiome to Improve Cardiometabolic Health.

Kristi M Crowe-White, Katelyn E Senkus, Janie C DiNatale

Abstract readReview
In one paragraph

Review in Nutrition reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kristi M Crowe-WhiteDepartment of Human Nutrition, The University of Alabama, Tuscaloosa, AL, 35401, United States.ORCID 0000-0003-2497-4582
Katelyn E SenkusUSDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, United States.
Janie C DiNataleDepartment of Human Nutrition, The University of Alabama, Tuscaloosa, AL, 35401, United States.

Funding

McCormick Science Institute
6 · The paper itself

Abstract

The intricate balance between the gut microbial ecosystem and cardiometabolic health underscores the importance of cultivating a healthy gut microbiome. A noteworthy strategy for harnessing the potential of this ecosystem is the consumption of prebiotics-non-digestible compounds promoting the growth of beneficial bacteria. While dietary polyphenols are emerging as significant modulators of microbial proliferation and systemic therapeutic effects, the prebiotic functionality of spice polyphenols remains understudied. It is, however, hypothesized that metabolism of spice polyphenols by intrinsic microflora in the colon may elicit downstream cardiometabolic effects resulting from the stimulated release of gut-derived metabolites, specifically short-chain fatty acids. This brief article highlights research on the functionality of spices, namely cinnamon and ginger, to influence microbial proliferation, the production of gut-derived metabolites and hormones, and prospective health outcomes.

Indexed as

Cardiovascular DiseasesGastrointestinal MicrobiomeSpicesCinnamomum zeylanicumFatty Acids, VolatileHumansPolyphenolsPrebioticsZingiber officinaleFatty Acids, VolatilePolyphenolsPrebioticscardiometaboliccinnamongingergut microbiomeshort-chain fatty acidsspices

Identifiers

PMID42186278
PMCPMC13201875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.