Evidence map›Paper›PMID 42186165›Full record

ReviewTuberculosis and respiratory diseases2026

Recent Updates on Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration and Its Clinical Implications.

Kyungjong Lee

Abstract readReview
In one paragraph

Review in Tuberculosis and respiratory diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kyungjong LeeDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. kj2011.lee@samsung.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the standard minimally invasive method for mediastinal staging in non-small cell lung cancer. As the tumor, node, metastasis (TNM) classification evolves with more refined prognostic stratification of N2 substages, accurate mediastinal evaluation has become increasingly critical. Beyond conventional staging, recent advances have significantly expanded the clinical utility of EBUS-TBNA. This review explores six key areas of development: evidence supporting systematic over targeted mediastinal sampling and the potential to omit confirmatory mediastinoscopy after negative EBUS-TBNA; the role of endoscopic ultrasound in accessing paraesophageal and inferior mediastinal stations; expanded procedural capabilities with third-generation thin scope EBUS; novel tissue acquisition devices, including the 19-gauge needle, mini forceps, and mediastinal cryobiopsy; considerations for tissue adequacy in next-generation sequencing; and image-based adjunctive tools such as elastography and artificial intelligence-driven sonographic analysis. Collectively, these developments underscore the growing role of EBUS-TBNA as a comprehensive diagnostic platform in thoracic oncology, extending its utility from mediastinal staging to peripheral lesion access, molecular profiling, and image-guided decision support.

Indexed as

CryobiopsyElastographyEndobronchial Ultrasound-Guided Transbronchial Needle AspirationLung CancerMediastinal StagingNext-Generation Sequencing

Identifiers

PMID42186165
PMCPMC13334114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.