Evidence map›Paper›PMID 42186123›Full record

ReviewJournal of integrative plant biology2026

Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation.

Guitao Zhong, Zhanchun Wang, Dingzhong Tang, Wei Wang

Abstract readReview
In one paragraph

Review in Journal of integrative plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Journal of fungi (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guitao ZhongState Key Laboratory of Agricultural and Forestry Biosecurity, Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Plant Immunity Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.ORCID https://orcid.org/0000-0003-1564-9630
Zhanchun WangState Key Laboratory of Agricultural and Forestry Biosecurity, Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Plant Immunity Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.ORCID https://orcid.org/0009-0000-6272-0060
Dingzhong TangState Key Laboratory of Agricultural and Forestry Biosecurity, Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Plant Immunity Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.ORCID https://orcid.org/0000-0001-8850-8754
Wei WangState Key Laboratory of Agricultural and Forestry Biosecurity, Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Plant Immunity Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.ORCID https://orcid.org/0000-0001-9027-1549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitogen-activated protein kinase (MAPK/MPK) cascades are conserved signaling modules that play crucial roles in plant growth, reproduction, and responses to biotic and abiotic stresses. Many breakthroughs have been made recently in understanding the functional and regulatory mechanisms involving MAPK cascades in plant immunity. In this review, we summarize the conserved composition and activation of MAPK cascades and update advances in understanding the molecular mechanisms by which plants maintain or inhibit MAPK activation. We also highlight the functional links between MAPK activation and other immune events, suggesting crosstalk in the plant immune signaling network. Furthermore, we outline the strategies by which pathogen effectors inhibit plant immunity by manipulating MAPK signaling and illuminate the contribution of MAPK cascades to effector-triggered immunity. Overall, this review provides major evidence for understanding the importance and complexity of MAPK signaling and reveals that the MAPK cascade serves as an essential signaling hub in activating plant immunity.

Indexed as

MAP Kinase Signaling SystemPlant ImmunityPlantsHost-Pathogen InteractionsMitogen-Activated Protein KinasesMitogen-Activated Protein KinasescascadekinaseMAPKplant immunityRaf‐likesignaling

Identifiers

PMID42186123
PMCPMC13446642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.