Evidence map›Paper›PMID 42186091›Full record

ArticleJournal of neuroinflammation2026

PVN

Hui Fang, An Liu, Jun-Fa Yang, Min Liu, Yin-Ying Zheng, Hong-Yan Zhang, Jin-Rong Guo, Piao-Piao Luo, Da-Shuai Yang, Rui Wang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroinflammation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hui Fang *School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
An Liu *School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Jun-Fa Yang *Department of Emergency Surgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230032, Anhui, China.
Min LiuSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Yin-Ying ZhengSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Hong-Yan ZhangSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Jin-Rong GuoSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Piao-Piao LuoSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Da-Shuai YangInflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, Anhui, China.
Rui WangSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Fu LaiSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Qiu-Ping ChenSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China.
Tao XuInflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, Anhui, China.
Hua WangInflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, 230032, Anhui, China. wanghua@ahmu.edu.cn.
Zhen-Hua RenSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, Anhui, China. renzhenhua1975@163.com.

Funding

Major Projects of the Ministry of Science and Technology of China 2021ZD0201102the National Natural Science Foundation of China 82071401
6 · The paper itself

Abstract

The central nervous system regulates glandular secretions by modulating visceral organ functions. However, the anatomical and functional connections between the brain and digestive enzyme-producing pancreatic acinar cells remain poorly defined. Using the hypertriglyceridemia-associated acute pancreatitis (HTGP) mouse model, we aimed to describe a functional transneuronal circuit connecting the hypothalamus to pancreatic acinar cells in mice. This circuit originates from a subpopulation of oxytocin neurons in the paraventricular hypothalamic nucleus (PVN

Indexed as

Acinar CellsParaventricular Hypothalamic NucleusVagus NerveAnimalsInflammationMaleMiceMice, Inbred C57BLNeuronsPancreatitisAcinar cellsFunctional transneuronal circuitInflammatory responsePancreas

Identifiers

PMID42186091
PMCPMC13386933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.