ArticleInfectious diseases of poverty2026
Heavy burden of soil-transmitted helminth infections in a remote and impoverished indigenous community of Honduras revealed by real time polymerase chain reaction.
Article in Infectious diseases of poverty, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSoil-transmitted helminths (STH) remain highly prevalent in Honduras, disproportionately affecting rural and underserved populations. Diagnostic limitations, particularly for Necator americanus and Strongyloides stercoralis, hinder accurate burden estimation. This study aimed to determine the prevalence and species distribution of STH infections using real-time polymerase chain reaction (PCR) in a remote, resource-limited setting.
methodsA rapid, non-representative cross-sectional survey was conducted among children and adults in a remote community in the Honduran Moskitia. Stool samples were analyzed using multiplex real-time PCR. Prevalence was estimated with 95% confidence intervals. Differences between groups were assessed using Fisher's exact test, and logistic regression models were used to explore associations of infection with age and sex. Ct values were summarized using medians and interquartile ranges.
resultsOverall community STH prevalence was 85.2% [95% confidence intervals (CI): 78.6-92.3], with 72.2% (95% CI: 58.4-83.5) in adults and 98.1% (95% CI: 90.1-100) in school-aged children, who were predominantly infected with Trichuris trichiura (77.8%, 95% CI: 69.9-85.7), followed by Ascaris lumbricoides (50.0%, 95% CI: 40.6-59.4), N. americanus (29.6%, 95% CI: 21.0-38.2), and S. stercoralis (3.7%, 95% CI: 0.1-7.3). Younger age and female sex were identified as significant risk factors for T. trichiura.
conclusionsThe extreme hyperendemicity of STH infections in the study community poses a serious health risk to its population, particularly children. These findings support the need for larger, systematically designed parasitological surveys that integrate sensitive diagnostic molecular tools to help precisely map STH epidemiology and guide control efforts in this and other underserved regions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.