Observational studyBMC public health2026
AI-based fundus screening of teachers: fundus tessellated density as a myopia biomarker and occupational associations.
Observational study in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Artificial intelligence-quantified fundus tessellated density and its association with myopia severity in Chinese children: a cross-sectional study.Frontiers in cell and developmental biology · 2026Article
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Authors and funding
14 authors.
Funding
Abstract
backgroundArtificial intelligence (AI)-based fundus imaging enables efficient large-scale retinal screening; however, its application in occupational populations remains limited.
objectiveTo evaluate the utility of an AI-based fundus screening system in teachers and to investigate fundus tessellated density (FTD) as a potential imaging marker associated with myopia and occupational factors.
methodsIn this prospective observational study, 648 teachers from Beijing underwent fundus photography and systemic examinations. AI algorithms were used to quantify FTD and other retinal parameters. Associations between spherical equivalent (SE), FTD, and systemic and occupational variables were assessed using univariate and multivariable regression analyses. Receiver operating characteristic (ROC) analysis was performed to evaluate the discriminative ability of FTD for high myopia.
resultsThe mean SE was - 2.43 ± 2.94 D, and mean FTD was 0.0609 ± 0.0743. FTD showed a non-uniform distribution across the macula, with higher values in the nasal quadrant. Multivariable analysis demonstrated that FTD, near-work duration at 30 cm, and ocular structural parameters were independently associated with SE (all P < 0.05). Prolonged near work (> 1 h) at 30 cm was associated with increased FTD. ROC analysis indicated moderate discriminative performance for high myopia (AUC = 0.7788 for overall FTD). In addition, FTD was associated with systemic immune-inflammatory indices, including NLR and PLR.
conclusionsAI-derived FTD may serve as a potential imaging marker associated with high myopia and occupational factors. These findings are observational and hypothesis-generating, and further longitudinal studies are required for validation.
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