Evidence map›Paper›PMID 42185749›Full record

ArticleAnalytical chemistry2026

InNMR: Direct

Amelie Frison, Marit M Sørensen, Kristoffer Prince, Maksim Mayzel, Finn L Aachmann, Gøril Eide Flaten, Philip Rainsford, Johan Isaksson

Abstract read
In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amelie FrisonDepartment of Pharmacy, UiT the Arctic University of Norway, Box 6050, Langnes, 9037 Tromsø, Norway.
Marit M SørensenDepartment of Pharmacy, UiT the Arctic University of Norway, Box 6050, Langnes, 9037 Tromsø, Norway.
Kristoffer PrinceDepartment of Pharmacy, UiT the Arctic University of Norway, Box 6050, Langnes, 9037 Tromsø, Norway.
Maksim MayzelBruker Switzerland AG, Industriestrasse 26, 8117 Fällanden, Switzerland.
Finn L AachmannDepartment of Biotechnology and Food Science, Norwegian University of Science and Technology (NTNU), Sem Sæland 6/8, 7491 Trondheim, Norway.ORCID 0000-0003-1613-4663
Gøril Eide FlatenDepartment of Pharmacy, UiT the Arctic University of Norway, Box 6050, Langnes, 9037 Tromsø, Norway.
Philip RainsfordDepartment of Chemistry, UiT the Arctic University of Norway, Box 6050, Langnes, 9037 Tromsø, Norway.
Johan IsakssonDepartment of Pharmacy, UiT the Arctic University of Norway, Box 6050, Langnes, 9037 Tromsø, Norway.ORCID 0000-0001-6287-7594

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel discoid insert that can be positioned into a standard NMR tube using an associated plunger tool has been developed. By attaching any type of semipermeable barrier to the bottom of the insert, the detection volume of the tube can be divided into two or more chambers, separated by a barrier of choice. Slice-selective experiments are then utilized to study a plethora of transport phenomena in real time by NMR spectroscopy. The technological device is presented together with a proof of concept for three different applications: permeability studies, diffusion-controlled pH titrations, and diffusion-controlled protein titrations. The developed approach unlocks new tools for scientists working in the fields of drug discovery, organic chemistry, biochemistry, chemical biology, microbiology, or electrochemistry that will enable new types of experiments to be performed by NMR spectroscopy.

Identifiers

PMID42185749
PMCPMC13261619

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.