Evidence map›Paper›PMID 42185542›Full record

ArticleNature methods2026

An encyclopedic regulatory and functional atlas of RNA interactomes.

Keren Zhou, Junhong Huang, Shurong Liu, Wujian Zheng, Shun Liu, Yinghao Xing, Yinan Cao, Yibo Chen, Xinping Hu, Li Cai and 11 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature methods, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. FMRP promotes gastric cancer progression via mJournal of translational medicine · 2026
    Article
  5. Article
  6. Article
  7. HuRInterDB: A Database Exploring the Landscape of lncRNA-Protein Interactions.Computational and structural biotechnology journal · 2026
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Keren Zhou *MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China. Keren.Zhou@stjude.org.ORCID http://orcid.org/0000-0001-7905-3399
Junhong Huang *MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Shurong Liu *MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Wujian Zheng *MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Shun Liu *Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, P. R. China.ORCID http://orcid.org/0000-0001-8850-9079
Yinghao XingMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Yinan CaoMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Yibo ChenMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Xinping HuMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Li CaiMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Jie ZhouMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Penghui LinMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Jiajia XuanMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Fangzhou XieMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.
Lahong XuGuangzhou National Laboratory, Guangzhou International Bio Island, Guangzhou, P. R. China.
Junhao LiDepartment of Cognitive Science, University of California, San Diego, CA, USA.ORCID http://orcid.org/0000-0001-6784-3780
Lingling ZhengMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China.ORCID http://orcid.org/0000-0002-7152-1095
Lianghu QuMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China. lssqlh@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-3657-2863
Jianjun ChenDepartment of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA. jianchen@coh.org.ORCID http://orcid.org/0000-0003-3749-2902
Bin LiMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China. libin73@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-5717-1551
Jianhua YangMOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, Innovation Center for Evolutionary Synthetic Biology, School of Life Sciences, Sun Yat-sen University, Guangdong, China. yangjh7@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-3863-2786

Funding

National Natural Science Foundation of China (National Science Foundation of China) 31970604National Natural Science Foundation of China (National Science Foundation of China) 32225011National Natural Science Foundation of China (National Science Foundation of China) 32370588National Natural Science Foundation of China (National Science Foundation of China) 32430019National Natural Science Foundation of China (National Science Foundation of China) 32470598
6 · The paper itself

Abstract

RNA molecules interact extensively with each other and with RNA-binding proteins (RBPs) to regulate gene expression. To improve detection of RBP-RNA and RNA-RNA interactions, we developed the rbsSeeker and rriScan tools and integrated the interactions into the Encyclopedia of RNA Interactomes (ENCORI), providing web-based modules to explore RNA interactions. Using this resource, we identified and validated novel N

Indexed as

RNARNA-Binding ProteinsAdenosineHumansMicroRNAsRNA MethylationAdenosineMicroRNAsN-methyladenosineRNARNA-Binding Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.