Evidence map›Paper›PMID 42185519›Full record

ArticleScientific reports2026

Phytochemical signatures and multifunctional bioactivities of two Ocimum basilicum varieties (Obb vs. Obg): antimicrobial, antioxidant, and anticancer potential.

Akram B Sultan, Khaled Haidar, Mohamed M Sayedahmed, Mohammed Hanafy, Gehan El-Akabawy, Amira A Ibrahim, Nermeen Foda, Mohamed Abdel-Haleem, Mohamed A Taha

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Akram B SultanDepartment of Biology, College of Science, University of Bisha, Bisha, 61922, Saudi Arabia.
Khaled HaidarDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, Bisha, 61922, Saudi Arabia.
Mohamed M SayedahmedDepartment of Microbiology and Botany, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Mohammed HanafyDepartment of Microbiology and Botany, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Gehan El-AkabawyDepartment of Basic Medical Sciences, College of Medicine, Ajman University, Ajman, United Arab Emirates.
Amira A IbrahimDepartment of Botany and Microbiology Faculty of Science, Arish University, Arish, Egypt. amiranasreldeen@sci.aru.edu.eg.
Nermeen FodaDepartment of Microbiology and Botany, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Mohamed Abdel-HaleemDepartment of Microbiology and Botany, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. mahafez@zu.edu.eg.
Mohamed A TahaDepartment of Microbiology and Botany, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study comparatively evaluated the phytochemical composition and biological activities of Ocimum basilicum var. basilicum (Obb) and Ocimum basilicum var. Genovese (Obg). Gas chromatography-mass spectrometry (GC-MS) analysis revealed notable qualitative and quantitative differences in key constituents, including fatty acids, alcohols, and aldehydes, which may influence their biological effects and therapeutic potential. Biological activities were assessed using multiple assays: antioxidant capacity via DPPH, ABTS, and FRAP methods; antibacterial activity against selected Gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa; and anticancer potential using the MTT assay on A431 epidermoid carcinoma cells. The results demonstrated that the Genovese variety (Obg) exhibited significantly higher antioxidant capacity and stronger antibacterial activity across all tested strains. In contrast, the basilicum variety (Obb) showed slightly greater cytotoxicity, with an IC

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsOcimum basilicumPhytochemicalsPlant ExtractsCell Line, TumorGas Chromatography-Mass SpectrometryHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsPhytochemicalsPlant ExtractsAnticancerAntimicrobialAntioxidant activityEssential oilsGC-MSGenovese basilMTT assayOcimum basilicumPhenolic compounds

Identifiers

PMID42185519
PMCPMC13201591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.