Evidence map›Paper›PMID 42185511›Full record

ArticleJournal of molecular histology2026

Icariin suppresses glycolysis in prostate cancer by upregulating ALKBH5 to mediate EARS2 m

HaiFeng Ying, Ming Ruan, WenHua Zhu, XiaoJing Wang

Abstract read
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In one paragraph

Article in Journal of molecular histology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

HaiFeng YingDepartment of Traditional Chinese Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai City, 200025, China.
Ming RuanDepartment of Traditional Chinese Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai City, 200025, China.
WenHua ZhuDepartment of Traditional Chinese Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai City, 200025, China.
XiaoJing WangDepartment of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No.197, Ruijin Second Road, Huangpu District, Shanghai City, 200025, China. XiaoJingwang564@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is among the most frequently occurring cancers in men. Its occurrence and progression are closely related to metabolic reprogramming, with abnormally active glycolysis being a notable feature sustaining rapid proliferation. Recent years have seen growing interest in the regulatory role of epigenetic modifications, particularly N⁶-methyladenosine (m

Indexed as

AlkB Homolog 5, RNA DemethylaseFlavonoidsGlycolysisProstatic NeoplasmsUp-RegulationAnimalsApoptosisCell Line, TumorCell MovementCell ProliferationCell SurvivalDemethylationEpitranscriptomeGene Expression Regulation, NeoplasticHumansMaleALKBH5 protein, humanAlkB Homolog 5, RNA DemethylaseFlavonoidsicariinALKBH5GlycolysisIcariinm6A modificationProstate cancer

Identifiers

PMID42185511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.