ArticleEye (London, England)2026
Predictors of the early pneumatic displacement effect of submacular haemorrhage secondary to polypoidal choroidal vasculopathy.
Article in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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15 authors.
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Abstract
purposeTo identify baseline predictors of early submacular haemorrhage (SMH) displacement following intravitreal injection of C3F8, recombinant tissue plasminogen activator (rt-PA), and ranibizumab in patients with polypoidal choroidal vasculopathy (PCV).
methodsIn this retrospective case-control study, swept-source OCT scans were analysed before and one week after treatment. SMH displacement was classified as incomplete (Group 1) or complete (Group 2) based on fundus photography and OCT. Clinical characteristics and OCT-derived parameters were evaluated for associations with displacement status.
resultsFifty-one eyes from 51 PCV patients were included. All eyes demonstrated some degree of SMH displacement after treatment, with 33 eyes showing incomplete displacement (residual SMH under the fovea: 80-768 μm) and 18 eyes showing complete displacement. Group 2 had better baseline visual acuity, and baseline LogMAR BCVA was negatively correlated with displacement grade. Group 2 also exhibited larger initial SMH volume and lower contrast-to-noise ratio (CNR), both associated with greater displacement. Although baseline PED volumes were similar, PED regression was more pronounced in Group 2.
conclusionComplete SMH displacement was associated with better baseline vision, lower CNR, larger haemorrhage volume, and greater PED regression. Baseline BCVA, CNR, and SMH volume may serve as predictive factors for early SMH displacement following treatment.
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