ArticleScientific reports2026
Quantitative and qualitative evaluation of residual deposits in implanted intravenous ports informs maintenance strategies.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
This study aimed to evaluate the distribution and composition of intraluminal deposits in implanted intravenous ports removed from oncology patients, with a focus on assessing the effectiveness of current nursing maintenance protocols. Ports removed after completion of cancer treatment were analyzed. Each catheter was segmented into proximal, middle, and distal thirds for regional analysis. Total protein concentrations were measured using the bicinchoninic acid (BCA) assay. Thrombosis-related proteins-fibrin, fibrinogen, thrombin, and P-selectin-were identified by Western blot analysis. A total of 46 patients were included. Three distinct patterns of protein residue distribution were identified between the injection chamber and the catheter. Eleven patients exhibited comparable protein levels in both regions, but only seven demonstrated adequate irrigation. Eighteen patients showed higher protein accumulation in the catheter, while seventeen had greater deposits in the injection chamber. The distal catheter segment consistently exhibited the highest protein concentration, particularly in ports implanted for more than five years. Western blot analysis confirmed the presence of thrombogenic proteins, and the absence of β-actin indicated minimal cellular debris. These findings suggest that mechanical flushing plays a more critical role than pharmacologic flushing in deposit clearance. Proteinaceous deposits persist despite adherence to current protocols, with a notable presence in areas of suboptimal flow, such as the chamber base and distal catheter. These findings suggest a link between flow dynamics and deposit accumulation, indicating that revisions to nursing guidelines-including standardized insertion, increased flushing volumes, and simulation-based competency training-may help support improved port function and potentially lower complication risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.