Evidence map›Paper›PMID 42185253›Full record

ArticleCell death discovery2026

ATP2B4 driven chromatin compaction exacerbates pancreatic cancer radiotherapy resistance.

Yuyu Luo, Wei Jiang, Yanfang Liu, Qinghua Li, Yuanfei Chen, Shiwan Lin, Hsiang-I Tsai, Lirong Zhang, Dongqing Wang, Xiang Liao and 1 more

Abstract read
In one paragraph

Article in Cell death discovery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuyu Luo *Institute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China.
Wei Jiang *Institute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China.
Yanfang Liu *Institute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China.
Qinghua LiInstitute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China.
Yuanfei ChenInstitute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China.
Shiwan LinInstitute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China.
Hsiang-I TsaiInstitute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China.
Lirong ZhangInstitute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China.
Dongqing WangInstitute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China. wangdongqing71@163.com.
Xiang LiaoInstitute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China. liaoxiang72@163.com.
Haitao ZhuInstitute of Medical Imaging and Artificial Intelligence, Jiangsu University, Zhenjiang, China. zhht25@163.com.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82071984National Natural Science Foundation of China (National Science Foundation of China) 82272066
6 · The paper itself

Abstract

The intrinsic radio-resistance of pancreatic cancer cells significantly hinders therapeutic efficacy. However, the precise molecular mechanisms underlying this resistance remain inadequately understood and warrant further investigation. Here, using the high-throughput metabolic CRISPR library screening and RNA sequencing, we identified an ATPase Plasma Membrane Ca

Identifiers

PMID42185253
PMCPMC13381861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.