ArticlePlacenta2026
Engineering the human placenta: Advances in modeling placental function.
Article in Placenta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The placenta is a highly specialized organ that mediates nutrient exchange, hormone production, and immune regulation at the maternal-fetal interface. Its dynamic architecture and function throughout gestation present significant challenges in studying placental biology and associated obstetric complications. Emerging developments in bioengineering offer innovative approaches to create physiologically relevant placental models that overcome the constraints of traditional in vitro and in vivo systems. This review highlights progress in microfluidic and organ-on-a-chip systems, spheroid and organoid models, bioengineered scaffolds, and in silico systems. We discuss how these platforms enable the investigation of trophoblast behavior and transport mechanisms and can even mimic the maternal-fetal barrier. By integrating principles of tissue engineering and materials science, advanced in vitro models hold immense promise for advancing our understanding of placental physiology, ultimately informing therapeutic strategies in maternal-fetal medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.