Evidence map›Paper›PMID 42184934›Full record

ArticleNeuropsychologia2026

Impacted and preserved sub-domains of cognitive control in schizophrenia.

Charlotte Li, Megan A Boudewyn, Deanna M Barch, Cameron S Carter, Michael J Frank, James M Gold, Angus W MacDonald, John D Ragland, Steven M Silverstein, Andrew Yonelinas and 2 more

Abstract read
In one paragraph

Article in Neuropsychologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Charlotte LiDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, United States.
Megan A BoudewynDepartment of Psychology, University of California, Santa Cruz, United States.
Deanna M BarchDepartment of Psychological & Brain Sciences, Washington University in St. Louis, United States.
Cameron S CarterDepartment of Psychiatry, University of California, Davis, School of Medicine, United States.
Michael J FrankDepartment of Cognitive, Linguistic, and Psychological Sciences, Brown University, United States.
James M GoldMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, United States.
Angus W MacDonaldDepartment of Psychology, University of Minnesota, United States.
John D RaglandDepartment of Psychiatry, University of California, Davis, School of Medicine, United States.
Steven M SilversteinDepartment of Psychiatry, University of Rochester Medical Center, United States.
Andrew YonelinasCenter for Mind & Brain and Department of Psychology, University of California, Davis, United States.
Steven J LuckCenter for Mind & Brain and Department of Psychology, University of California, Davis, United States.
Molly A EricksonDepartment of Psychiatry & Behavioral Neuroscience, University of Chicago, United States. Electronic address: merickson1@uchicago.edu.

Funding

Cognitive Neurocomputational Task Reliability and Clinical Applications ConsortiumR01MH084840 · NIMH · WASHINGTON UNIVERSITY · PI Deanna Barch, Cameron S. Carter · 2008 to 2026
$8.5M
4/5-Cognitive Neuroscience Task Reliability & Clinical Applications ConsortiumR01MH084821 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLD, JAMES M. · 2008 to 2023
$4.2M
2/5-Cognitive Neuroscience Task Reliability & Clinical Applications ConsortiumR01MH084826 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI CARTER, CAMERON S. · 2008 to 2023
$4.0M
5/5-Cognitive Neuroscience Task Reliability & Clinical Applications ConsortiumR01MH084861 · NIMH · UNIVERSITY OF MINNESOTA · PI MACDONALD, ANGUS W · 2008 to 2024
$3.8M
Cognitive Neurocomputational Task Reliability & Clinical Applications ConsortiumR01MH084828 · NIMH · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SILVERSTEIN, STEVEN M · 2008 to 2024
$3.3M
NIMH NIH HHS R01 MH084821NIMH NIH HHS R01 MH084826NIMH NIH HHS R01 MH084828NIMH NIH HHS R01 MH084840NIMH NIH HHS R01 MH084861
6 · The paper itself

Abstract

Cognitive control refers to the ability to dynamically guide behavior by maintaining goal context and filtering out irrelevant information. Cognitive control deficits are well-documented in people with schizophrenia (PSZ), but the degree of impairment varies considerably depending upon the type of control being assessed. The present study examined three domains of cognitive control-selective attention to context, rule switching, and response conflict management-within a single paradigm to characterize different facets of cognitive control dysfunction in PSZ. Thirty-eight PSZ and 35 healthy control subjects (HCS) completed a cued task-switching paradigm that required participants to make a button-press response to different features of a target stimulus (letter, number, or color) depending upon the location that the target appeared on each trial. Prior to target onset, participants were presented with a cue indicating which stimulus dimension would be probed. PSZ were able to utilize the cue as effectively as HCS; however, when the relevant target dimension switched between trials (thus requiring a different stimulus-response mapping), PSZ showed greater switch costs compared to HCS. Finally, PSZ showed modestly impaired response conflict management when the irrelevant stimulus dimensions of the target corresponded to a different (incongruent) response compared to the relevant stimulus dimension. These findings suggest that selective attention to context is mostly intact, but response rule switching and response conflict management are impaired in PSZ.

Indexed as

Cognition DisordersExecutive FunctionSchizophreniaSchizophrenic PsychologyAdultAttentionConflict, PsychologicalCuesFemaleHumansMaleMiddle AgedNeuropsychological TestsPhotic StimulationReaction TimeYoung Adult

Identifiers

PMID42184934
PMCPMC13283411

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.