Evidence map›Paper›PMID 42184900›Full record

ArticleContemporary clinical trials2026

Rationale and protocol for time-based energy intake goals within an obesity care lifestyle intervention: Daily eating patterns for total health study.

Hollie A Raynor, Kristoffer S Berlin, Dale S Bond, Chelsi Cardoso, Mary Carskadon, Samantha Ehrlich, Emilie Holloway, John G Thomas, Yin Wu

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hollie A RaynorThe University of Tennessee Knoxville, Department of Nutrition, 1215 W. Cumberland Ave., 229 Jessie Harris Building, Knoxville, TN 37996, USA. Electronic address: hraynor@utk.edu.
Kristoffer S BerlinThe University of Memphis, Department of Psychology, 352 Psychology Building, Memphis, TN 38152, USA. Electronic address: ksberlin@memphis.edu.
Dale S BondHartford Hospital, Center for Obesity Research, Innovation, and Education, Digestive Health Institute, Hartford HealthCare, 80 Seymour St., Hartford, CT 06102, USA. Electronic address: dale.bond@hhchealth.org.
Chelsi CardosoThe University of Tennessee Knoxville, Department of Nutrition, 1215 W. Cumberland Ave., 229 Jessie Harris Building, Knoxville, TN 37996, USA. Electronic address: ccardoso@vols.utk.edu.
Mary CarskadonBradley Hospital, Sleep for Science Research Laboratory, 300 Duncan Dr., Providence, RI 02906, USA. Electronic address: mary_carskadon@brown.edu.
Samantha EhrlichThe University of Tennessee Knoxville; Department of Kinesiology, Recreation, and Sport Studies, 1914 Andy Holt Ave., 330 HPER Building, Knoxville, TN 37996, USA. Electronic address: sehrlic1@utk.edu.
Emilie HollowayThe University of Tennessee Knoxville, Department of Nutrition, 1215 W. Cumberland Ave., 229 Jessie Harris Building, Knoxville, TN 37996, USA. Electronic address: ehollow5@vols.utk.edu.
John G ThomasThe Miriam Hospital & Warren Alpert Medical School of Brown University, Weight Control and Diabetes Research Center, 196 Richmond St.; Providence, RI 02903, USA. Electronic address: john_g_thomas@brown.edu.
Yin WuHartford Hospital, Center for Obesity Research, Innovation, and Education, Digestive Health Institute, Hartford HealthCare, 80 Seymour St., Hartford, CT 06102, USA. Electronic address: yin.wu@hhchealth.org.

Funding

Effect of time-based energy intake goals on weight loss during obesity treatment.R01DK137752 · NIDDK · UNIVERSITY OF TENNESSEE KNOXVILLE · PI Hollie A Raynor · 2024 to 2026
$1.9M
NIDDK NIH HHS R01 DK137752
6 · The paper itself

Abstract

This publication outlines the rationale and protocol for the Daily Eating Patterns for Total Health (DEPTH) trial, detailing its motivation, aims, design, intervention, and measures. This randomized clinical trial examines how time-based energy goals applied within a 12-month obesity care lifestyle intervention influences percent weight loss, dietary temporal patterns, sleep regularity, and appetite regulation. One hundred seventy-four adults (ages: 25-60 y; BMI: 27-45 kg/m

Indexed as

Energy IntakeFeeding BehaviorLife StyleObesityAdultAppetite RegulationBody Mass IndexExerciseFemaleGoalsHumansMaleMiddle AgedRandomized Controlled Trials as TopicSleepTime FactorsChrononutritionCircadian entrainmentLifestyle interventionObesity careSleep regularityTime-based energy intake

Identifiers

PMID42184900
PMCPMC13287975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.