Evidence map›Paper›PMID 42184240›Full record

ArticleNeonatology2026

Oxygen Saturation Targeting and Retinopathy Management in Very Preterm Neonates: An International Survey.

Brian A Darlow, Elizabeth M Hurrion, Malcolm Battin, Mikael Norman, Mark Adams, Alina Kowalczykiewicz-Kuta, Tetsuya Isayama, Gil Klinger, Laura San Feliciano, Valerie Biran and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neonatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Brian A DarlowDepartment of Paediatrics, University of Otago, Christchurch, New Zealand.
Elizabeth M HurrionDepartment of Newborn Services, Mater Mothers' Hospital, Brisbane, Queensland, Australia.
Malcolm BattinNewborn Service, Health New Zealand, Te Whatu Ora, Auckland City Hospital, Auckland, New Zealand.
Mikael NormanDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Mark AdamsDepartment of Neonatology, University and University Hospital Zurich, Zurich, Switzerland.
Alina Kowalczykiewicz-KutaDepartment of Neonatology, University of Opole, Opole, Poland.
Tetsuya IsayamaDivision of Neonatology, National Center for Child Health and Development, Tokyo, Japan.
Gil KlingerDepartment of Neonatal Intensive Care, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.
Laura San FelicianoUnidad de Neonatología, Hospital Universitario de Salamanca, Salamanca, Spain.
Valerie BiranService de Pédiatrie et Réanimation Néonatales, Hôpital Universitaire Robert-Debré, Université de Paris-Cité, Paris, France.
Marco MoroniNeonatal Intensive Care Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
Jamil Pedro de Siqueira CaldasUniversidade Estadual de Campinas (UNICAMP), Hospital da Mulher Prof. Dr. J. A. Pinotti-Caism, Campinas, Brazil.
Dirk BasslerDepartment of Neonatology, University and University Hospital Zurich, Zurich, Switzerland.
Satoshi KusudaNeonatal Research Network of Japan, Kyorin University, Tokyo, Japan.
Maximo VentoDivision of Neonatology, Health Research Institute Hospital La Fe, Valencia, Spain.
Brian ReichmanGertner Institute for Epidemiology and Health Policy Research, Sheba Medical Centre, Ramat Gan, Israel.
Neha GoswamiDepartment of Pediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada.
Prakesh S ShahDepartment of Pediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada, prakeshkumar.shah@sinaihealth.ca.
Kei LuiNational Perinatal Epidemiology and Statistics Unit, University of New South Wales, Randwick, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVariation in the uptake of evidence-based practices and adoption of unproven therapies by neonatal intensive care units (NICUs) might contribute to clinical variability. The objective was to survey current oxygen saturation targets (SpO

methodsOnline pre-piloted anonymous questionnaires on care practices in 2023 for extremely preterm (<29 weeks) infants were sent to the directors of 608 NICUs in the iNeo. Four questions concerned ROP management and results were compared with a similar 2015 survey.

resultsThere were 11 participating networks from 12 high-income countries and one from a middle-income country. The overall NICU response rate was 63% (382 units). Despite variability between NICUs, within networks, there was limited change in SpO DISCUSSION: There was considerable variation in care practices between NICUs, and the relationship of this to clinical outcomes should be explored.

Indexed as

Anti-vascular endothelial growth factorNeonatal networksOxygen saturation targetsRetinopathy of prematurityVery preterm infants

Identifiers

PMID42184240
PMCPMC13363109

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.