Evidence map›Paper›PMID 42184085›Full record

ArticleHead and neck pathology2026

Caught in the Act: Intercalated Duct Lesion Associated with Adenoid Cystic Carcinoma Harboring a MYBL1::NFIB Fusion.

André Lametti, Seungwon Kim, Raja R Seethala

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Head and neck pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

André LamettiDepartment of Pathology and Laboratory Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. lamettia@upmc.edu.ORCID http://orcid.org/0000-0003-0110-0727
Seungwon KimDepartment of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Raja R SeethalaDepartment of Pathology and Laboratory Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0003-3617-075X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intercalated duct lesions (IDLs) are putative precursors notably associated with epithelial myoepithelial carcinoma and basal cell adenoma. We report the novel transition of IDL to adenoid cystic carcinoma (AdCC) in the parotid gland of a 38-year-old male. The patient presented with a longstanding mass and subsequently underwent parotidectomy. Microscopically, the 3.9 cm tumor consisted mainly of tubular/cribriform AdCC. However, the periphery showed three IDL foci with a similar immunophenotype. Next generation sequencing demonstrated a MYBL1::NFIB fusion. We thus further expand the spectrum of tumors that can transition from IDL.

Indexed as

Carcinoma, Adenoid CysticOncogene Proteins, FusionParotid NeoplasmsAdultHumansMaleMYB-NFIB fusion protein, humanOncogene Proteins, FusionCarcinoma, Adenoid CysticIntercalated DuctMYBL1 protein humanSalivary Glands/pathology

Identifiers

PMID42184085
PMCPMC13201694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.