Evidence map›Paper›PMID 42183897›Full record

ArticleMikrochimica acta2026

Photo-triggered g-C

Huiling Xue, Guorong Cheng, Bing Zhang, Ying Zhan, Zhihuan Zhao, Jianying Lin, Yan Cheng

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huiling XueCollege of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Guorong ChengCollege of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Bing ZhangCollege of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China. zhangbing01@tyut.edu.cn.
Ying ZhanCollege of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Zhihuan ZhaoCollege of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Jianying LinCollege of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Yan ChengDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, 030001, China. chengyan_1976@163.com.

Funding

Natural Science Foundation of Shanxi Province 20210302123142
6 · The paper itself

Abstract

Carbohydrate antigen 19 - 9 (CA19-9) is a critical biomarker in clinical oncology, as its serum concentration is closely associated with tumor detection and therapeutic monitoring. In this study, a novel colorimetric immunoassay was developed for the sensitive detection of CA19-9, utilizing g-C₃N₄/Ag₂S nanocomposites as a photoactive signal probe. The nanocomposites, synthesized via a hydrothermal method, demonstrated strong absorption in the visible region and high photocatalytic activity. In the immunoassay, antibody-functionalized magnetic beads were used to capture the target antigen, followed by labeling with detection probes based on the g-C₃N₄/Ag₂S nanocomposites. Under visible light irradiation, the nanocomposites catalyzed the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB), producing a distinct color change that was quantitatively analyzed via UV-vis spectroscopy. The method exhibited a wide linear detection range from 4.0 to 400 U/mL, with a detection limit of 1.86 U/mL, and demonstrated excellent specificity, stability, and reproducibility. Successful application to human serum samples further validated the reliability and practical utility of the assay, highlighting its promising potential for clinical cancer diagnosis and screening.

Indexed as

CA-19-9 AntigenColorimetryGraphiteNanocompositesSilver CompoundsAntibodies, ImmobilizedBenzidinesHumansImmunoassayLimit of DetectionNitrogen CompoundsPhotochemical Processes3,3',5,5'-tetramethylbenzidineAntibodies, ImmobilizedBenzidinesCA-19-9 AntigenGraphitegraphitic carbon nitrideNitrogen CompoundsSilver CompoundsCA19-9Colorimetric detectiong-C3N4/Ag2SImmunoassayNanocomposite

Identifiers

PMID42183897

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.