Evidence map›Paper›PMID 42183872›Full record

ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2026

Energy metabolism and adenylate system in Mytilus galloprovincialis (Lamarck, 1819) tissues under acute hypoxia.

A S Osipova, A A Soldatov, N E Shalagina, I V Golovina, Yu V Bogdanovich, V N Rychkova

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nanozinc Ecotoxicity in the Freshwater Invasive BivalveAnimals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A S OsipovaAnimal Physiology and Biochemistry Department, A.O. Kovalevsky Institute of Biology of the Southern Seas of RAS, Nakhimov Ave, 2, Sevastopol, 299011, Russia. kohan-alena@inbox.ru.ORCID http://orcid.org/0000-0002-0891-0362
A A SoldatovAnimal Physiology and Biochemistry Department, A.O. Kovalevsky Institute of Biology of the Southern Seas of RAS, Nakhimov Ave, 2, Sevastopol, 299011, Russia.ORCID http://orcid.org/0000-0002-9862-123X
N E ShalaginaAnimal Physiology and Biochemistry Department, A.O. Kovalevsky Institute of Biology of the Southern Seas of RAS, Nakhimov Ave, 2, Sevastopol, 299011, Russia.ORCID http://orcid.org/0000-0001-6195-6135
I V GolovinaAnimal Physiology and Biochemistry Department, A.O. Kovalevsky Institute of Biology of the Southern Seas of RAS, Nakhimov Ave, 2, Sevastopol, 299011, Russia.ORCID http://orcid.org/0000-0003-1199-7339
Yu V BogdanovichAnimal Physiology and Biochemistry Department, A.O. Kovalevsky Institute of Biology of the Southern Seas of RAS, Nakhimov Ave, 2, Sevastopol, 299011, Russia.ORCID http://orcid.org/0000-0002-8239-4968
V N RychkovaAnimal Physiology and Biochemistry Department, A.O. Kovalevsky Institute of Biology of the Southern Seas of RAS, Nakhimov Ave, 2, Sevastopol, 299011, Russia.ORCID http://orcid.org/0000-0003-3797-715X

Funding

Russian Academy of Sciences 124030100137-6
6 · The paper itself

Abstract

The present study investigated the impact of acute hypoxia on key enzymes and products of energy metabolism in Mytilus galloprovincialis (Lamarck, 1819) tissues under experimental conditions. The response to hypoxia was tissue-specific. We found that anaerobic processes increased in the gills and foot, where the concentrations of glucose and pyruvate increased. In the gills, this was accompanied by higher succinate dehydrogenase (SDH) and aldolase activities. Concurrently, in the foot we observed a significant decrease in lactate dehydrogenase (LDH) activity and no change in lactate concentration, indicating suppression of the glucose-lactate metabolic pathway. At the same time, both tissues exhibited a significant increase in octopine dehydrogenase (OcDH) activity, indicating a shift of metabolism to the glucose-opine (octopine) pathway under hypoxia. The hepatopancreas acted as a donor of carbohydrate substrates. Glucose and lactate contents there decreased significantly. Metabolic reorganisation was accompanied by a decrease in ATP content in all tissues, a decrease in the adenylate pool and a loss of adenylate energy charge (AEC), indicating low efficiency of the glucose-opine pathway which is typical of the genus Mytilus.

Indexed as

Energy MetabolismHypoxiaMytilusAdenosine TriphosphateAmino Acid OxidoreductasesAnimalsGillsGlucoseHepatopancreasLactic AcidL-Lactate DehydrogenaseSuccinate DehydrogenaseAdenosine TriphosphateAmino Acid OxidoreductasesD-octopine dehydrogenaseGlucoseLactic AcidL-Lactate DehydrogenaseSuccinate DehydrogenaseAcute hypoxiaAdenylate systemGlycolytic enzymesGlycolytic metabolitesMytilus galloprovincialisSuccinate dehydrogenase

Identifiers

PMID42183872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.