Evidence map›Paper›PMID 42183579›Full record

ArticleAnalytical chemistry2026

Nanopipettes Enable Native Mass Spectrometry Studies of the Intrinsically Disordered Protein α-Synuclein in Biochemical Buffers.

Emily J Byrd, Emma L Norgate, Joel A Crossley, Chalmers C C Chau, Bob Schiffrin, Alexander Kulak, Sheena E Radford, Paolo Actis, Antonio N Calabrese, Frank Sobott

Abstract read
In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emily J ByrdAstbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0002-9876-1400
Emma L NorgateAstbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K.
Joel A CrossleyAstbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0002-6656-1578
Chalmers C C ChauSchool of Electronic and Electrical Engineering, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0002-3134-6798
Bob SchiffrinAstbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K.
Alexander KulakSchool of Chemistry, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0002-2798-9301
Sheena E RadfordAstbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0002-3079-8039
Paolo ActisSchool of Electronic and Electrical Engineering, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0002-7146-1854
Antonio N CalabreseAstbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0003-2437-7761
Frank SobottAstbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0001-9029-1865

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buffer and electrolyte conditions

Indexed as

alpha-SynucleinIntrinsically Disordered ProteinsNanotechnologySpectrometry, Mass, Electrospray IonizationBuffersHumansProtein Conformationalpha-SynucleinBuffersIntrinsically Disordered Proteins

Identifiers

PMID42183579
PMCPMC13261622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.