ArticleFrontiers in psychology2026
Altered regional homogeneity in Parkinson's disease with mild cognitive impairment: a resting-state fMRI study.
Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: To explore changes in regional homogeneity (ReHo) of brain function in patients with Parkinson's disease with mild cognitive impairment (PD-MCI) using resting-state functional magnetic resonance imaging (rs-fMRI), and to analyze the correlation between ReHo values in differential brain regions and cognitive function, so as to identify potential neuroimaging biomarkers for PD-MCI. Methods: A total of 43 patients with PD were enrolled and divided into the PD-MCI group ( Results: Compared with the PD-NC group, the PD-MCI group showed significantly decreased ReHo values in the right middle frontal gyrus and right superior frontal gyrus ( Conclusion: Functional abnormalities in brain regions including the right middle frontal gyrus, right superior frontal gyrus, right cerebellar lobule VIII, left inferior temporal gyrus, and right fusiform gyrus are closely associated with the occurrence and development of PD-MCI. ReHo indicators in these regions are promising potential neuroimaging biomarkers for auxiliary diagnosis and monitoring the progression of PD-MCI.
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