Evidence map›Paper›PMID 42183484›Full record

ArticleBiomaterials research2026

Anti-senescence Effects of Nanovesicles Derived from Cluster of Differentiation-146-Positive Tonsil Mesenchymal Stem Cells via Modulation of the Tumor Protein 53 Pathway.

Dohyun Kim, Hong Bae Jeon, Kyu-Sik Shim, Jeong Su Park, Jeong-Kee Yoon, Jun Hee Lee, Jeong-Hui Park, Jang-Hyun Park, Jieun Kim, Jinseo Yoon and 2 more

Abstract read
In one paragraph

Article in Biomaterials research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dohyun KimPLCOskin Co., Ltd, Seoul 03721, Republic of Korea.ORCID https://orcid.org/0009-0003-5530-2161
Hong Bae JeonDepartment of Medicine, Yonsei University Graduate School, Seoul 07322, Republic of Korea.
Kyu-Sik ShimPLCOskin Co., Ltd, Seoul 03721, Republic of Korea.
Jeong Su ParkPLCOskin Co., Ltd, Seoul 03721, Republic of Korea.
Jeong-Kee YoonDepartment of Systems Biotechnology, Chung-Ang University, Anseong, Gyeonggi 17546, Republic of Korea.
Jun Hee LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Chungnam 31116, Republic of Korea.
Jeong-Hui ParkInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Chungnam 31116, Republic of Korea.
Jang-Hyun ParkInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Chungnam 31116, Republic of Korea.
Jieun KimDepartment of Biological Science, Research Institute of Women's Health, Brain Korea 21 Project, Sookmyung Women's University, Seoul 04310, Republic of Korea.
Jinseo YoonDepartment of Biological Science, Sookmyung Women's University, Seoul 04310, Republic of Korea.
Jung Bok LeeDepartment of Biological Science, Research Institute of Women's Health, Brain Korea 21 Project, Sookmyung Women's University, Seoul 04310, Republic of Korea.
Wooyeol BaekPLCOskin Co., Ltd, Seoul 03721, Republic of Korea.ORCID https://orcid.org/0000-0002-6638-4110

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging greatly contributes to the progressive dysfunction of tissues and organs that accompany the aging process. Recently, nanovesicles derived from tonsil mesenchymal stem cells (TMSC-NVs) were investigated for their potential to reverse cellular senescence. However, the molecular mechanisms through which TMSC-NVs prevent senescence remain unclear. In the present study, we focused on Cluster of Differentiation 146 (CD146), a surface marker used to identify specific MSC subgroups and examined the anti-senescence effects of CD146-positive TMSC-NVs (CD146

Identifiers

PMID42183484
PMCPMC13191092

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.