Evidence map›Paper›PMID 42183478›Full record

ArticleApplied physics reviews2025

Feeling the vibes: Vibrational spectroscopic imaging of biomolecular assemblies in their natural environment.

Zhongyue Guo, Giulio Chiesa, Ji-Xin Cheng

Abstract read
In one paragraph

Article in Applied physics reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhongyue GuoDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA.ORCID 0009-0008-0780-186X
Giulio ChiesaDepartment of Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3E2, Canada.ORCID 0000-0001-7077-5934
Ji-Xin ChengDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA.ORCID 0000-0002-5607-6683

Funding

Vibrational Spectroscopic Imaging to Unveil Hidden Signatures in Living SystemsR35GM136223 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CHENG, JI-XIN · 2020 to 2025
$5.7M
NIGMS NIH HHS R35 GM136223
6 · The paper itself

Abstract

Biomolecular assemblies form via intramolecular interactions and serve important biological functions. The most characterized biomolecular assemblies are amyloid fibrils, which are associated with neurodegenerative diseases. Advances in microscopy techniques enabled characterization of the morphology of these assemblies, but so far, failed in detailed structural characterizations. Vibrational spectroscopic imaging presents unique advantages to studying biomolecular assemblies in their natural environment due to the sensitivity of vibrational spectra to protein structural changes, especially

Identifiers

PMID42183478
PMCPMC13196607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.