Evidence map›Paper›PMID 42183438›Full record

ArticleMedical science educator2026

Cognitive Load in Virtual Reality Anatomy Education: Comparing 2D and 3D Learning Experiences.

Brandon Lowry, Samantha McGrath, Chad Eitel, Kenneth Ivie, Carolyn Meyer, Becky Wiltgen, Heather Hall, Landon Williams, Samantha Scherner, Tod Clapp

Abstract read
In one paragraph

Article in Medical science educator, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Brandon Lowry *Department of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.ORCID 0009-0007-7614-7585
Samantha McGrath *Department of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.
Chad EitelDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.
Kenneth IvieDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.
Carolyn MeyerDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.
Becky WiltgenDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.
Heather HallDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.
Landon WilliamsDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.
Samantha SchernerDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.
Tod ClappDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO USA.ORCID 0009-0008-9102-7896

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With virtual reality (VR) becoming increasingly integrated into educational settings, it remains crucial to understand how different formats of educational content impact cognitive processing. This study examined the impact of 2D versus 3D VR modules on cognitive load and learning outcomes in undergraduate anatomy education. Using real-time biometric measurements collected through VR head-mounted displays, cognitive load was assessed as students observed recorded laryngeal anatomy modules presented by virtual instruction utilizing 2D images or 3D models. Despite no significant impact on learning outcomes, participants in the 2D group consistently demonstrated a higher mean cognitive load (M = 0.58, SD = 0.05) compared to the 3D group (M = 0.49, SD = 0.07), indicating a significant reduction in cognitive effort with 3D visualization. Pre- and post-survey results revealed a mixed landscape in perceptions of VR technology, with some students reporting positive views and comfort, while others expressed significant reservations. Notably, however, no significant difference was found between individually reported attitudes and cognitive load, suggesting that students' cognitive load during the intervention was independent of these variables. Further, prior experience with VR, video game use, and general attitudes toward technology did not significantly influence cognitive load, suggesting that instructional design had a more substantial impact than user familiarity. These findings support the pedagogical value of incorporating 3D VR in anatomy curricula and highlighted the importance of evidence-based design to improve learning outcomes while managing cognitive demand. Supplementary Information: The online version contains supplementary material available at 10.1007/s40670-026-02655-1.

Indexed as

3D visualizationAnatomy educationBiometric measurementCognitive loadInstructional designLearning outcomesVirtual reality

Identifiers

PMID42183438
PMCPMC13197557

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.