ArticleResearch square2026
Astrocytic but not Microglial Antigen Presentation Shapes Protective Immunity to Toxoplasma gondii in the Brain.
Sydney A Labuzan, Anne E Schuster, Michael A Kovacs, Maureen N Cowan, Mark J Lawson, Isaac W Babcock, Lydia A Sibley, Abigail G Kelly, Anne E Marchildon, Tajie H Harris
Abstract readPreprint
In one paragraphArticle in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Sydney A LabuzanUniversity of Virginia.
Anne E SchusterUniversity of Virginia.
Michael A KovacsUniversity of Virginia.
Maureen N CowanUniversity of Virginia.
Mark J LawsonUniversity of Virginia.
Isaac W BabcockUniversity of Virginia.
Lydia A SibleyUniversity of Virginia.
Abigail G KellyUniversity of Virginia.
Anne E MarchildonUniversity of Virginia.
Tajie H HarrisUniversity of Virginia.
Funding
INFECTIOUS DISEASES TRAINING PROGRAMT32AI007046 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Alison K Criss, William A Petri · 1985 to 2026
$15.3MMEDICAL SCIENTIST TRAINING PROGRAMT32GM007267 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GARCIA-BLANCO, MARIANO A. · 1985 to 2024
$13.4MINTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2MBIOTECHNOLOGY TRAINING PROGRAMT32GM008715 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LAURIE, GORDON WILLIAM · 2000 to 2019
$6.6MAlarmin-mediated control of CNS infectionR01NS112516 · NINDS · UNIVERSITY OF VIRGINIA · PI HARRIS, TAJIE H. · 2020 to 2023
$1.9MCaspase-8 mediated control of CNS infectionR01NS134747 · NINDS · UNIVERSITY OF VIRGINIA · PI TAJIE H. HARRIS · 2024 to 2026
$1.5MBrain, Immunology and Glia Training ProgramT32NS115657 · NINDS · UNIVERSITY OF VIRGINIA · PI Alban P Gaultier, TAJIE H. HARRIS · 2021 to 2026
$1.2MThe role of meningeal lymphatic vasculature in regulating immunity and intracranial pressure during central nervous system infectionF30AI154740 · NIAID · UNIVERSITY OF VIRGINIA · PI KOVACS, MICHAEL · 2021 to 2021
$51kNIAID NIH HHS F30 AI154740NIAID NIH HHS T32 AI007046NIAID NIH HHS T32 AI007496NIGMS NIH HHS T32 GM007267NIGMS NIH HHS T32 GM008715NINDS NIH HHS R01 NS112516NINDS NIH HHS R01 NS134747NINDS NIH HHS T32 NS115657
6 · The paper itselfAbstract
T cells play a pivotal role in orchestrating immune defense within the central nervous system (CNS) during many infections.
Indexed as
Antigen PresentationAstrocytesMicrogliaNeuroimmunologyToxoplasma gondii
Identifiers
PMID42183379
PMCPMC13193102
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