Evidence map›Paper›PMID 42183369›Full record

ArticleResearch square2026

Immune cells during compensatory renal hypertrophy after unilateral nephrectomy.

Shishir Kumar Patel, Qisen Guo, Mahta Gooya, Ryo Matsuura, Hyun Jun Jung, Radhika Kapoor, Tara Fallah Rastegar, Sanjeev Noel, Hamid Rabb

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shishir Kumar PatelJohns Hopkins University School of Medicine.
Qisen GuoJohns Hopkins University School of Medicine.
Mahta GooyaJohns Hopkins University School of Medicine.
Ryo MatsuuraJohns Hopkins University School of Medicine.
Hyun Jun JungJohns Hopkins University School of Medicine.
Radhika KapoorJohns Hopkins University School of Medicine.
Tara Fallah RastegarJohns Hopkins University School of Medicine.
Sanjeev NoelJohns Hopkins University School of Medicine.
Hamid RabbJohns Hopkins University School of Medicine.

Funding

Acute Kidney Injury and Double Negative T CellsR01DK104662 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HAMAD, ABDEL RAHIM, RABB, HAMID · 2015 to 2023
$3.8M
Acute kidney injury and microbiomeR01DK123342 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI RABB, HAMID · 2020 to 2024
$3.0M
TIGIT in acute kidney injury and repairR01DK132278 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI Sanjeev Noel · 2023 to 2026
$1.9M
NIDDK NIH HHS R01 DK104662NIDDK NIH HHS R01 DK123342NIDDK NIH HHS R01 DK132278
6 · The paper itself

Abstract

The mechanisms underlying compensatory renal hypertrophy (CRH) in living kidney donors after unilateral nephrectomy (UNx) remain complex and underexplored. We examined immune cells involved in CRH after UNx in mice. Following UNx of the left kidney in WT mice, GFR measurements, flow cytometry, and single-cell RNA sequencing were performed over 8 weeks. Rag1

Indexed as

Compensatory renal hypertrophy (CRH)Glomerular filtration rate (GFR)Kidney mononuclear cells (KMNCs)Unilateral nephrectomy (UNx)

Identifiers

PMID42183369
PMCPMC13193141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.