Evidence map›Paper›PMID 42183365›Full record

ArticleResearch square2026

Learning Beyond the Clinic: Can Point of Choice Visual Feedback Prompts Elicit Motor Behavior Changes in Persons with Multiple Sclerosis?

Samantha R Fox, David C Jangraw, Guido Mascia, Reed D Gurchiek, Yuanyuan Feng, Brett M Meyer, Andrew J Solomon, Ellen W McGinnis, Ryan S McGinnis

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samantha R FoxUniversity of Vermont.
David C JangrawUniversity of Vermont.
Guido MasciaWake Forest University School of Medicine.
Reed D GurchiekClemson University.
Yuanyuan FengUniversity of Vermont.
Brett M MeyerUniversity of Vermont.
Andrew J SolomonThe Larner College of Medicine at the University of Vermont.
Ellen W McGinnisWake Forest University School of Medicine.
Ryan S McGinnisWake Forest University School of Medicine.

Funding

Just-In-Time Fall Prevention: Development of an mHealth Intervention for Persons with Multiple SclerosisR21EB027852 · NIBIB · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI MCGINNIS, RYAN S. · 2019 to 2021
$610k
NIBIB NIH HHS R21 EB027852
6 · The paper itself

Abstract

Background: Falls are common in persons with multiple sclerosis (PwMS), and their consequences further undermine their quality of life. Current fall prevention interventions fail to address real-time stability challenges that may occur during cognitively complex daily activities. This need may be fulfilled by means of just-in-time interventions that leverage prompts delivered via a mobile app, having the aim of producing beneficial targeted biomechanical changes. Methods: Fourteen ambulatory PwMS completed multiple Timed Up-and-Go tests under cognitive load across two different visits. Two visual feedback prompts targeting trunk flexion during sit-to-stand transitions (STS-TF) and stance width (SW) during gait were delivered terminally via ab Results: Prompts were successfully able to systematically reduce STS-TF by 7.1° (p < 0.001, d = - 0.483) and to increase SW by 8.1 mm (p = 0.021, d = 0.259). The majority of participants reported willingness to use the app with and without physician prescription (95% and 68%, respectively). Conclusion: This study demonstrated for the first time that PwMS can produce targeted biomechanical adaptations in response to point-of-choice visual feedback prompts delivered by a mobile app, supporting that just-in-time mobile interventions as a proactive fall prevention strategy.

Indexed as

fall preventionmobile healthMultiple sclerosispoint-of-choice interventionstance widthtrunk flexionvisual feedback

Identifiers

PMID42183365
PMCPMC13193110

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.