Evidence map›Paper›PMID 42183083›Full record

ArticleNature. Mental health2023

Association of Probable Post-Traumatic Stress Disorder with Dietary Pattern and Gut Microbiome in a Cohort of Women.

Shanlin Ke, Xu-Wen Wang, Andrew Ratanatharathorn, Tianyi Huang, Andrea L Roberts, Francine Grodstein, Laura D Kubzansky, Karestan C Koenen, Yang-Yu Liu

Abstract read
In one paragraph

Article in Nature. Mental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shanlin KeChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Xu-Wen WangChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Andrew RatanatharathornDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA.
Tianyi HuangChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Andrea L RobertsDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Francine GrodsteinRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612, USA.
Laura D KubzanskyDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Karestan C KoenenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Yang-Yu LiuChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.

Funding

Therapeutic Control of Aspirin-Exacerbated Respiratory DiseaseU19AI095219 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Joshua A Boyce · 2011 to 2026
$29.1M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Multi-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthmaUH3OD023268 · OD · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2018 to 2022
$13.5M
Prospective Study of the Gut Microbiome in AgingRF1AG067744 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI CHAN, ANDREW T · 2020 to 2020
$11.7M
Post Traumatic Stress Disorder and Accelerated Aging in WomenR01MH101269 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C, KUBZANSKY, LAURA D · 2014 to 2021
$6.5M
Functional Redundancy of Human Microbiome and its Implication in Fecal Microbiota TransplantationR01AI141529 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI LIU, YANG-YU · 2019 to 2023
$4.5M
Long-term health consequences of birth by cesarean sectionR01HD093761 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO · 2018 to 2022
$3.3M
NHLBI NIH HHS U01 HL089856NIAID NIH HHS R01 AI141529NIAID NIH HHS U19 AI095219NIA NIH HHS RF1 AG067744NICHD NIH HHS R01 HD093761NIH HHS UH3 OD023268NIMH NIH HHS R01 MH101269
6 · The paper itself

Abstract

Post-Traumatic Stress Disorder (PTSD) is a psychiatric condition that may occur in people who have experienced or witnessed traumatic events. The microbiota-gut-brain axis has been suggested to play an important role in mental health. Here we analyzed information on trauma exposure and PTSD symptoms with the gut microbiome data and dietary information in 191 individuals enrolled in a substudy of an ongoing longitudinal cohort of women. We demonstrated that higher PTSD symptom levels were associated with less adherence to the Mediterranean diet pattern, and this association was also linked to specific PTSD putative protective species such as

Identifiers

PMID42183083
PMCPMC13195745

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.