ReviewJournal of pain research2026
Pain Catastrophizing: Mechanisms and Clinical Implications.
Review in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to summarize current perspectives on the underlying mechanisms, conceptual frameworks, and potential clinical implications of pain catastrophizing (PC). Methods: A narrative review approach was employed. Results: Existing studies suggest that PC may be associated with functional activity in several brain regions, including the anterior cingulate cortex, amygdala, and prefrontal cortex, which are involved in pain perception and emotional regulation. From a psychosocial perspective, catastrophizing has been linked to psychological distress, social support, and behavioral responses to pain. Various interventions, including psychological therapies, pain neuroscience education, exercise-based approaches, and complementary therapies have been explored as potential strategies for addressing PC. However, findings across studies remain heterogeneous. Discussion: This study integrates current evidence on neurobiological mechanisms and psychosocial models related to PC and discusses their potential clinical implications. By summarizing existing findings and highlighting areas of uncertainty, this work aims to provide a more comprehensive understanding of the multidimensional nature of PC and may inform future research and clinical approaches in chronic pain management.
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