Evidence map›Paper›PMID 42183020›Full record

ArticleBiological theory2026

Mind Everywhere: A Framework for Conceptualizing Goal-Directedness in Biology and Other Domains-Part Two.

Michael Levin, David B Resnik

Abstract read
In one paragraph

Article in Biological theory, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael LevinAllen Discovery Center, Tufts University, Medford, MA, USA.ORCID 0000-0001-7292-8084
David B ResnikNational Institute of Environmental Health Ethics, National Institutes of Health, North Carolina, USA.ORCID 0000-0002-5139-9555

Funding

Ethical, social, and legal issues in environmental health researchZIAES102646 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI RESNIK, DAVID · 2009 to 2025
$1.8M
Intramural NIH HHS ZIA ES102646
6 · The paper itself

Abstract

What makes a system-evolved, engineered, or hybrid-describable by teleological and mentalistic terms such as intelligent, goal-directed, cognitive, and intentional? In this two-part article, we review classical thought on teleology in the life sciences and defend a new approach to goal-directedness that stems from an emerging field-diverse intelligence. This field seeks to characterize what all active agents, regardless of their composition or provenance, have in common. Our approach emphasizes: (1) empirical testability (not philosophical commitments to linguistic categories), (2) fecundity in discovery of new capabilities (not just reductive mechanistic explanations of results after they are made, but worldviews that facilitate and enable novel research), (3) operationalization of terminology by reference to conceptual and empirical toolkits shown to be effective for a given system (cognitive and teleological claims are really hypotheses of optimal interaction protocols), and (4) continuity of human goal-directedness with our unicellular origins (which implies a need for models of scaling of cognition). In Part One, we reviewed historical and contemporary debates about teleology in biology and described some ground-breaking experimental results from morphogenesis, synthetic biology, and other areas of research involving the coordination of cellular behavior by means of bioelectric networks. In Part Two, we argue that current approaches to goal-directedness in biology cannot accommodate these results in a manner that helps us better understand how these systems work and fruitfully guides experimental work and practical applications in these areas of research. What is needed, therefore, is an approach to teleology in biology, informed by mentalistic concepts, such as intelligence, cognition, and intentionality. We describe and explain our mentalistic approach in greater depth, show how it can be applied to specific cases, and address some important objections to our view. By abandoning the reductionistic aversion to mentalistic concepts in biology in favor of principled and testable frameworks for understanding diverse minds embodied in the physical world, the plasticity and problem-solving competency of the agential material of life can provide fodder for advances in philosophical thought, as well as for biomedical and bioengineering applications.

Indexed as

AgencyBioengineeringBiomedicineDevelopmental biologyDiverse intelligencePhilosophyTeleology

Identifiers

PMID42183020
PMCPMC13196611

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.