ArticleTherapeutic advances in infectious disease
Knowledge, attitudes, and practices on antibiotic use and antimicrobial resistance among graduating health care professionals at Debre Tabor University, Ethiopia: a cross-sectional study with implications for antimicrobial stewardship education.
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Abstract
Background: Rational use of antimicrobials is a key strategy for preventing antimicrobial resistance (AMR) and relies primarily on the knowledge and practices of future health care professionals. Objectives: To assess the knowledge, attitudes, and practices of graduating health care students regarding antibiotic use and AMR at Debre Tabor University. Design: An institution-based cross-sectional study was employed. Methods: The study was conducted from March to April 2025 among graduating students at the College of Health Sciences. A validated self-administered questionnaire was used to assess knowledge, attitude, and practice (KAP). Scores were categorized using previous studies and modified Bloom's cut-off criteria (⩾80% = good; <80% = poor). Data were analyzed using descriptive statistics, chi-square tests, pearson correlation, and logistic regression, with Results: Antibiotic use in the past year was reported by 75.2% of participants, with ciprofloxacin and amoxicillin being the most commonly used agents. Overall, 55.8% showed good knowledge, 41.3% had a positive attitude and 51.4% reported good practices. While awareness of AMR was high, only 32.5% correctly identified antimicrobial stewardship (AMS). A total of 68% of students purchased antibiotics without a prescription, and 69.9% discontinued treatment once symptoms improved. Significant differences in KAP across departments were observed ( Conclusion: The study showed that 55.8% of respondents had good knowledge, but attitudes (41.3%) and practices (51.4%) were lower, highlighting a clear knowledge-practice gap and the need for strengthened AMS training.
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