Evidence map›Paper›PMID 42182835›Full record

ArticleOpen forum infectious diseases2026

Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Pediatric Patient.

Phung Nguyen The Nguyen, Nguyen Thanh Hung, Ngo Ngoc Quang Minh, Nguyen Thi Thu Hong, Nguyen Thi Thanh Huong, Cao Minh Hiep, Le Nguyen Thanh Nhan, Tran Van Dinh, Du Tuan Quy, Tran Thanh Thuc and 20 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Phung Nguyen The NguyenUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0003-2444-1786
Nguyen Thanh HungChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Ngo Ngoc Quang MinhChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Nguyen Thi Thu HongOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0009-0004-4993-6616
Nguyen Thi Thanh HuongChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Cao Minh HiepChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Le Nguyen Thanh NhanChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Tran Van DinhChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Du Tuan QuyChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Tran Thanh ThucUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0001-8809-2699
Tran Minh NhutChildren's Hospital 1, Ho Chi Minh City, Vietnam.
Nguyen Thi Han NyOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Lam Anh NguyetUniversity of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Le Nguyen Truc NhuOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Do Duong Kim HanOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Truong Hoang Chau TrucOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Le Thi Tam UyenHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Nghiem My NgocHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Tran Nguyen Phuong ThaoHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Tran Thi Thanh TamHospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Sandy Tze-Minn MakA*STAR Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore.
Jurre Y SiegersInstitut Pasteur du Cambodge, Cambodia.ORCID https://orcid.org/0000-0002-0246-7830
Sebastian Maurer-StrohA*STAR Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore.ORCID https://orcid.org/0000-0003-0813-9640
Nguyen Thanh DungA*STAR Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore.
Erik A KarlssonInstitut Pasteur du Cambodge, Cambodia.ORCID https://orcid.org/0000-0001-6004-5671
Guy ThwaitesOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Chee Wah TanInfectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Nguyen Van Vinh ChauDepartment of Health, Ho Chi Minh City, Vietnam.
Le Van TanOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0002-1791-3901
SEACOVARIANTS and H5N1 Consortia

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel clade 2.3.2.1e A(H5N1) virus was detected in cerebrospinal fluid but not in respiratory, rectal swab, or blood samples of an 8-year-old boy presenting with meningoencephalitis without respiratory symptoms. Cerebrospinal fluid A(H5N1) hemagglutinin-specific antibody levels were higher than those of sera. Clinicians should be aware of emerging clade 2.3.2.1e A(H5N1)-associated meningoencephalitis.

Indexed as

H5N1highly pathogenic avian influenzameningoecephalitisVietnam

Identifiers

PMID42182835
PMCPMC13197838

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.