Evidence map›Paper›PMID 42182696›Full record

ArticleJournal of thoracic disease2026

Short-term gaseous and particulate air pollution exposure and risk of acute kidney injury: a 12-year case-crossover study [2013-2024] in Guangzhou, China.

Yuqi Chen, Zhiman Liang, Keran Zhang, Wenhan Cao, Youpeng Chen, Chengtao Zhou, Guanghui Dong, Baoqing Sun, Zhangkai J Cheng

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuqi Chen *National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou Laboratory, Guangzhou, China.
Zhiman Liang *National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou Laboratory, Guangzhou, China.
Keran Zhang *National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou Laboratory, Guangzhou, China.
Wenhan Cao *Department of Clinical Laboratory, Dermatology Hospital, Southern Medical University, Guangzhou, China.
Youpeng ChenNational Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou Laboratory, Guangzhou, China.
Chengtao ZhouNational Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou Laboratory, Guangzhou, China.
Guanghui DongGuangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Baoqing SunNational Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou Laboratory, Guangzhou, China.
Zhangkai J ChengNational Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou Laboratory, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute kidney injury (AKI) is a major public health burden associated with high morbidity, significantly increasing long-term mortality, and escalating healthcare costs. While long-term air pollution exposure is a known risk factor for chronic kidney disease (CKD), evidence regarding the acute triggers of AKI remains limited, especially in Asian megacities with complex pollution profiles. We investigated the independent effects of major air pollutants on the risk of AKI using algorithmically identified clinical data. Methods: A time-stratified case-crossover study was conducted involving adults in Guangzhou, China [2013-2024]. We included patients with longitudinal serum creatinine records and strictly excluded those with end-stage renal disease (ESRD) or a history of kidney transplantation. AKI events were defined using the Kidney Disease: Improving Global Outcomes (KDIGO) serum creatinine criteria. Daily meteorological and air pollutant data were collected from respective monitoring stations. Conditional logistic regression and generalized additive models were employed to estimate the associations between short-term exposure to fine particulate matter [particulate matter less than 2.5 μm (PM Results: A total of 10,857 AKI cases (60.0% male; 62.2% aged <65 years) were included. In multi-pollutant models, gaseous pollutants showed robust independent associations with AKI. A 10 µg/m Conclusions: Short-term exposure to ambient SO

Indexed as

Acute kidney injury (AKI)air pollutioncase-crossover studynitrogen dioxide (NO2)sulfur dioxide (SO2)

Identifiers

PMID42182696
PMCPMC13190152

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.