Evidence map›Paper›PMID 42182688›Full record

ArticleJournal of thoracic disease2026

Oncologic outcomes after declining lung cancer surgery: mixed methods analysis of a prospective pilot cohort.

Robert M Van Haren, Alique Topalian, Melinda Butsch Kovacic, Sofia W Viana, Allison Moore, Catherine G Pratt, Shesh Rai, John Kues

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert M Van HarenCincinnati Research in Outcomes and Safety in Surgery (CROSS) Research Group, Division of Thoracic Surgery, Department of Surgery, University of Cincinnati, Cincinnati, OH, USA.
Alique TopalianUniversity of Cincinnati Cancer Center, Cincinnati, OH, USA.
Melinda Butsch KovacicUniversity of Cincinnati Cancer Center, Cincinnati, OH, USA.
Sofia W VianaCincinnati Research in Outcomes and Safety in Surgery (CROSS) Research Group, Division of Thoracic Surgery, Department of Surgery, University of Cincinnati, Cincinnati, OH, USA.ORCID https://orcid.org/0000-0003-4899-8685
Allison MooreCincinnati Research in Outcomes and Safety in Surgery (CROSS) Research Group, Division of Thoracic Surgery, Department of Surgery, University of Cincinnati, Cincinnati, OH, USA.
Catherine G PrattCincinnati Research in Outcomes and Safety in Surgery (CROSS) Research Group, Division of Thoracic Surgery, Department of Surgery, University of Cincinnati, Cincinnati, OH, USA.
Shesh RaiCincinnati Research in Outcomes and Safety in Surgery (CROSS) Research Group, Division of Thoracic Surgery, Department of Surgery, University of Cincinnati, Cincinnati, OH, USA.
John KuesDepartment of Family and Community Medicines, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The standard treatment for early-stage non-small cell lung cancer (NSCLC) is lung cancer resection. Unfortunately, some patients decline to undergo recommended surgery. The aim of this study is to evaluate patient oncologic outcomes after declining surgery. Methods: Patients were enrolled in a prospective, mixed-methods study. Surveys and semi-structured interviews assessed patient-provider relationships and outcomes. Qualitative analysis identified key themes, and mixed-methods analyses compared those who received surgery with those who declined surgery. Results: The cohort included 29 patients with NSCLC (63 years, 55% male, 59% White and 41% Black race). A participant survey indicated that food insecurity (n=6, 21%), lack of reliable transportation (n=4, 14%), and housing instability (n=2, 7%) were common. Five patients (17%) declined the recommended surgery and were more likely to be Black and have low-income (all P<0.05). They also reported poor patient-physician relationships reporting lack of trust in their physician (n=3, 60%) and inadequate communication (n=2, 40%). Qualitative analysis identified common themes among patients who declined surgery, such as lack of understanding of cancer and previous poor relationships with physicians, which impacted their decision to decline surgery. Patients who declined cancer surgery had treatment delays (60% Conclusions: Declining recommended lung cancer surgery was associated with lower income, Black race, poorer patient-physician relationships along with treatment delays, and worse overall survival. Interventions are needed to strengthen patient-provider relationships to improve lung cancer outcomes for all patients.

Indexed as

decline surgeryLung cancerpatient-physician communication

Identifiers

PMID42182688
PMCPMC13190079

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.