ArticleJournal of thoracic disease2026
Clinical and computed tomography (CT) features of nodular pulmonary histoplasmosis.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pulmonary histoplasmosis is a fungal infection caused by Histoplasma capsulatum. Although endemic in certain regions, it is increasingly reported worldwide. Nodular pulmonary histoplasmosis (NPHP) represents a distinct form of the disease, characterized by the formation of granulomatous nodules within the lung parenchyma of the host. Clinically, patients may present with nonspecific symptoms or remain entirely asymptomatic, and the condition can mimic various other pulmonary diseases. High-resolution computed tomography (HRCT) plays a crucial role in identifying characteristic nodular patterns, which aids in differentiating NPHP from other pulmonary nodules. This study aimed to analyze the HRCT features and clinical characteristics of patients with NPHP to enhance clinicians' awareness of this entity in the differential diagnosis of pulmonary nodules. Methods: A retrospective analysis was conducted on the clinical data, chest computed tomography (CT) imaging findings, and pathological features of 23 patients diagnosed with NPHP in our hospital from January 2014 to May 2024. Results: Among the 23 patients, males were more common (16 cases, 69.57%). The average age of NPHP was 50.30±13.07 years, and most of them had no clinical symptoms. NPHP was observed in the left lung in 9 cases (39.13%) and in the right lung in 14 cases (60.87%). Additionally, the minimum distance from the pleura measured approximately 4.28±5.45 mm. Twenty-two cases (95.65%) showed solid nodules (SNs), 17 cases (73.91%) were isolated lesions in the lungs, 15 cases (65.22%) had round-shaped lesions, 19 cases (82.61%) had clear borders, 10 cases (43.48%) exhibited lobulated growth patterns, 6 cases (26.09%) had spiculated margins, and 15 cases (65.22%) demonstrated adhesion to the pleura. Conclusions: NPHP exhibits a higher prevalence among male patients. The majority of cases are asymptomatic and bilateral lungs can be involved. Lesions are predominantly subpleural and adhere to the pleura, presenting as solitary, well-defined SNs with a round-like appearance. Abnormal bronchi, vascular signs, cavities, and calcifications are infrequently observed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.