Evidence map›Paper›PMID 42182518›Full record

ArticlebioRxiv : the preprint server for biology2026

Tract-explainable and underexplained synchrony play complementary roles in the functional organization of the brain.

Jiebin Luo, Xin Zeng, Yue Xiong, Yuanhang Xu, Changsong Zhou, Yanjiang Wang, Dezhong Yao, Daqing Guo

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiebin LuoClinical Hospital of Chengdu Brain Science Institute, MOE-K Lab for NeuroInformation, Brain-Apparatus Communication Institute, University of Electronic Science and Technology of China, Chengdu 611731, China.
Xin ZengClinical Hospital of Chengdu Brain Science Institute, MOE-K Lab for NeuroInformation, Brain-Apparatus Communication Institute, University of Electronic Science and Technology of China, Chengdu 611731, China.
Yue XiongClinical Hospital of Chengdu Brain Science Institute, MOE-K Lab for NeuroInformation, Brain-Apparatus Communication Institute, University of Electronic Science and Technology of China, Chengdu 611731, China.
Yuanhang XuClinical Hospital of Chengdu Brain Science Institute, MOE-K Lab for NeuroInformation, Brain-Apparatus Communication Institute, University of Electronic Science and Technology of China, Chengdu 611731, China.
Changsong ZhouDepartment of Physics, Centre for Nonlinear Studies, Hong Kong Baptist University, Kowloon Tong, Hong Kong.
Yanjiang WangCollege of Control Science and Engineering, China University of Petroleum (East China), Qingdao 266580, Shandong Province, China.
Dezhong YaoClinical Hospital of Chengdu Brain Science Institute, MOE-K Lab for NeuroInformation, Brain-Apparatus Communication Institute, University of Electronic Science and Technology of China, Chengdu 611731, China.
Daqing GuoClinical Hospital of Chengdu Brain Science Institute, MOE-K Lab for NeuroInformation, Brain-Apparatus Communication Institute, University of Electronic Science and Technology of China, Chengdu 611731, China.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Macroscale functional connectivity emerges from a complex interplay between structural wiring and non-tract-mediated mechanisms. However, the intrinsic entanglement of these contributions obscures their specific roles in brain organization. Here, we introduce a computational modeling framework to disentangle functional synchrony into two fundamentally distinct components: tract-explainable and tract-underexplained synchrony. Validated across two large-scale human cohorts (

Indexed as

functional organizationlarge-scale brain modelTract-explainable synchronytract-underexplained synchrony

Identifiers

PMID42182518
PMCPMC13192678

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.