ArticlebioRxiv : the preprint server for biology2026
Divergent signaling profiles in mTOR gain-of-function Smith-Kingsmore syndrome (SKS) and TSC2 deficiency.
Curtis R Carlson, Yang Shen, Hongzhi He, Erwin K Gudenschwager, Chunyan Hou, Junfeng Ma, Joanna C Chiu, Andrew C Liu
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Curtis R CarlsonDepartment of Entomology and Nematology, College of Agricultural and Environmental Sciences, University of California, Davis, CA 95616, USA.ORCID 0000-0003-2927-5019 Yang ShenDepartment of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA.
Hongzhi HeDepartment of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA.
Erwin K GudenschwagerDepartment of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA.
Chunyan HouDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.
Junfeng MaDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.
Joanna C ChiuDepartment of Entomology and Nematology, College of Agricultural and Environmental Sciences, University of California, Davis, CA 95616, USA.
Andrew C LiuDepartment of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA.ORCID 0000-0003-1927-0900 Funding
UC Davis MCB T32 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) MentorshipT32GM007377 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEDIN, FREDERIC LOUIS · 1985 to 2023
$9.9MNon-transcriptional regulation of circadian physiologyR01DK124068 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOANNA Chungyen CHIU · 2019 to 2026
$3.1MThe UC Davis enhanced Molecular, Cellular, and Developmental Biology Training ProgramT32GM153586 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Frederic Louis Chedin, ELVA D DIAZ · 2024 to 2026
$2.3MRole of mTOR in Circadian and Sleep Deregulation in Smith-Kingsmore Syndrome (SKS)R01NS117457 · NINDS · UNIVERSITY OF FLORIDA · PI Andrew C. Liu · 2023 to 2026
$1.8MNutrient-sensitive protein modifications regulate daily biological rhythmsR21AG082480 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIU, JOANNA CHUNGYEN · 2024 to 2025
$443kInvestigating the molecular mechanisms underlying sleep disruption in Smith-Kingsmore SyndromeF31NS147396 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Curtis Ryan Carlson · 2026 to 2026
$43kNIA NIH HHS R21 AG082480NIDDK NIH HHS R01 DK124068NIGMS NIH HHS T32 GM007377NIGMS NIH HHS T32 GM153586NINDS NIH HHS F31 NS147396NINDS NIH HHS R01 NS117457
6 · The paper itselfAbstract
Smith-Kingsmore syndrome (SKS) is a rare neurodevelopmental disorder caused by gain-of-function mutations in
Identifiers
PMID42182492
PMCPMC13192592
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