Evidence map›Paper›PMID 42182439›Full record

ArticlebioRxiv : the preprint server for biology2026

Pyramidal-cell-specific hemispheric asymmetry shapes dorsoventral CA1 dynamics during rest and exploratory behavior.

Chung Sub Kim, Jackson Banks, Miswakumari Lad, Seungwoo Kang

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chung Sub KimDepartment of Neuroscience & Regenerative Medicine, Medical College of Georgia at Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-2039-3476
Jackson BanksDepartment of Neuroscience & Regenerative Medicine, Medical College of Georgia at Augusta University, Augusta, GA 30912, USA.
Miswakumari LadDepartment of Neuroscience & Regenerative Medicine, Medical College of Georgia at Augusta University, Augusta, GA 30912, USA.
Seungwoo KangCenter for Neuroimmunology and Glial Biology, Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, TX 77030, USA.

Funding

Astrocyte-neuron mechanisms of glutamatergic modulation in social novelty recognitionR01MH137204 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Seungwoo Kang · 2024 to 2026
$1.2M
Role of hippocampal HCN Channels in social avoidanceR01MH134958 · NIMH · AUGUSTA UNIVERSITY · PI Chung Sub Kim · 2024 to 2026
$1.1M
NIMH NIH HHS R01 MH134958NIMH NIH HHS R01 MH137204
6 · The paper itself

Abstract

The hippocampus is organized along dorsal-ventral and left-right axes, but whether and how these axes interact within defined neuronal populations across behavioral states remains unresolved. Here, we combined within-animal slice electrophysiology with dual-site fiber photometry to compare dorsal and ventral CA1 activity across contralateral hemispheric configurations in mice expressing CaMKIIα-jGCaMP8s and SynI-jRCaMP1b at distinct longitudinal sites. Ventral CA1 pyramidal neurons exhibited greater intrinsic excitability and stronger AMPAR-mediated synaptic responses than dorsal CA1 neurons.

Indexed as

CA1CaMKIIαfiber photometryhemispheric asymmetryHippocampusOpen field test

Identifiers

PMID42182439
PMCPMC13192602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.