Evidence map›Paper›PMID 42182283›Full record

ArticlebioRxiv : the preprint server for biology2026

Serotype-dependent differences in AAV cellular transduction rates in the hypothalamus of Arctic ground squirrels.

B W Laughlin, M H Sugiura, D Tupone, L E Fenno, M M Weltzin

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

B W LaughlinInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK, USA.ORCID 0000-0001-6948-1314
M H SugiuraInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK, USA.
D TuponeDepartment of Neurological Surgery, Oregon Health & Science University, Portland, OR, USA.
L E FennoPsychiatry & Neuroscience, University of Texas at Austin, Austin TX, USA.
M M WeltzinInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK, USA.

Funding

Renovation of LARS for Arctic Ground Squirrel BreedingP20GM130443 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI KELLY L DREW · 2019 to 2026
$16.4M
NIGMS NIH HHS P20 GM130443
6 · The paper itself

Abstract

Adeno-associated viral (AAV) vectors are foundational tools for dissecting brain structure-function relationships, but AAV serotype tropism varies across brain regions and species, requiring empirical validation to inform experimental design. This need is especially important in non-model organisms, where molecular neuroscience tools remain underdeveloped and access to research subjects is often limited. The Arctic ground squirrel (AGS,

Indexed as

adeno-associated virusarctic ground squirrelgene deliveryhibernationhypothalamusviral tropism

Identifiers

PMID42182283
PMCPMC13192803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.