Evidence map›Paper›PMID 42182221›Full record

ArticlebioRxiv : the preprint server for biology2026

δ-catenin controls layer-specific transcriptional maturation of astrocytes via Zbtb20.

Gabrielle Séjourné, Christabel X Tan, Justin T Savage, Gracie Manigault, Grace Richards Jane Ding, Evelyn J Hardin, Juan Ramirez, Ryan Baumert, Kristina Sakers, Cagla Eroglu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabrielle SéjournéDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Christabel X TanDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Justin T SavageDepartment of Neurobiology, Duke University School of Medicine, Durham, NC 27710, USA.
Gracie ManigaultHoward Hughes Medical Institute, Duke University, Durham, NC 27710, USA.
Grace Richards Jane DingDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Evelyn J HardinDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Juan RamirezDepartment of Neurobiology, Duke University School of Medicine, Durham, NC 27710, USA.
Ryan BaumertDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Kristina SakersDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Cagla ErogluDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0002-7204-0218

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
Novel Genetically Encoded Indicators for Interrogating Neuron-Astrocyte Communication Across TimescalesU19NS123719 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI TIAN, LIN · 2021 to 2025
$10.7M
Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
Control of Astrocyte Development and Astrocyte-Synapse InteractionsR01NS102237 · NINDS · DUKE UNIVERSITY · PI EROGLU, CAGLA · 2018 to 2022
$1.9M
How does neuronal contact mediate astrocyte transcriptional maturation?F31NS134252 · NINDS · DUKE UNIVERSITY · PI SAVAGE, JUSTIN · 2023 to 2025
$125k
American Heart Association-American Stroke Association 25PRE1357000NIGMS NIH HHS T32 GM007171NIGMS NIH HHS T32 GM145449NINDS NIH HHS F31 NS134252NINDS NIH HHS R01 NS102237NINDS NIH HHS U19 NS123719
6 · The paper itself

Abstract

Coordinated maturation of diverse neural cell types drives mammalian cortical circuit development. Disruption of this coordination is a hallmark of human neurodevelopmental disorders, yet mechanisms that synchronize transcriptional maturation across cell types remain poorly understood. Here, we identify δ-catenin (

Indexed as

astrocytesCerebral cortexCUT&RUNdelta-cateninneurodevelopmentsingle-nuclei RNA sequencingspatial transcriptomicstranscriptional regulationZbtb20

Identifiers

PMID42182221
PMCPMC13192610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.