Evidence map›Paper›PMID 42182042›Full record

ArticleCurrent research in food science2026

Integrated metabolome and transcriptome reveal the molecular basis of flavonoid pathway-mediated fruit firmness variation in sweet cherry (

Yanlin Li, Zhen Yan, Jing Li, Huimin Chen, Xin Hua, Shengnan Tan, Yanqiang Gao, Yazhou Zhao, Baojiang Zheng, Xuwei Duan and 5 more

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Article in Current research in food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Yanlin LiMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Zhen YanMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Jing LiMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Huimin ChenMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Xin HuaMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Shengnan TanMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Yanqiang GaoMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Yazhou ZhaoMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Baojiang ZhengMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Xuwei DuanInstitute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Xiaoming ZhangInstitute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Guohua YanInstitute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Kaichun ZhangInstitute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Zheyong XueMinistry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, China.
Jing WangInstitute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sweet cherry is rich in diverse bioactive compounds and functional nutrients. Fruit firmness is a key determinant of postharvest storability, shelf life, and commercial value. Secondary metabolism is one of the important factors regulating sweet cherry fruit firmness, yet the molecular mechanisms underlying the regulation of firmness by secondary metabolism remain unclear. We performed integrated transcriptomic and untargeted metabolomic analyses at four key developmental stages using two cultivars with contrasting firmness: soft-fleshed 'Shangnan2808' and hard-fleshed 'Wanhongzhu'. We also conducted bulked metabolomic analysis on extreme firmness phenotypes from an F1 segregating population derived from these two parents. Fruit firmness differed significantly from color break to full ripeness stage, with epidermal cell thickness and mesocarp cell packing density identified as major structural contributors. KEGG enrichment revealed that flavonoid biosynthesis was the most significantly enriched pathway among six pathways containing 41 stable differential metabolites. Multi-omics integration identified 186 differentially expressed genes involved in these pathways. Among them, the flavanone 3-hydroxylase-like gene

Indexed as

Flavonoid biosynthesisFruit firmnessFruit qualityMetabolomicsSweet cherry (Prunus avium)Transcriptomics

Identifiers

PMID42182042
PMCPMC13195287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.