ArticleRadiology case reports2026
Adult-onset neuroblastic tumor: An extremely rare entity in the adult population.
Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The neuroblastic tumor spectrum (NTS) encompasses a group of extracranial neoplasms arising from neural crest derived cells of the sympathetic nervous system. Although neuroblastoma, the most undifferentiated subtype, is one of the most common solid tumors in the pediatric population, NTs of any subtype are exceedingly rare in adults. Ganglioneuroblastoma represents an intermediate entity within the NT spectrum, characterized by immature neuroblasts and maturing ganglion cells, and demonstrates heterogeneous clinical behavior. Radiologically, NTs present as a large, multilobulated, heterogeneously enhancing and solid masses. Imaging must be supplemented with laboratory and pathological study to achieve a definitive diagnosis. We report the case of a 33-year-old male with adult-onset lumbosacral ganglioneuroblastoma. This case highlights the importance of correlating imaging with histopathological and laboratory study to diagnose this entity that is exceedingly rare in adults.
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