ReviewGastro hep advances2026
Genetic Epidemiology of Hepatitis B Virus in Africa: A Review.
Review in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Hepatitis B virus (HBV) is an enveloped and hepatotoxic virus belonging to the hepadnaviridae family, and it has the potential to cause both acute and chronic hepatitis. HBV remains a major public health threat, particularly in Asia, Africa, and South America, resulting in several deaths even though there is currently a safe vaccine against it. Methods: This systematic review examined the geographic distribution of HBV genotypes across Africa. We conducted a literature search on the major databases using key search strategies and a thorough combination of terms for HBV genotype distribution, from January 1, 2014, to January 31, 2025. Results: The findings revealed varying HBV genetic diversity in African regions, with some studies demonstrating similar or consistent results. Genotypes A, D, and E were commonly reported. However, genotype E was the most predominant, while genotype A was highly variable across the continent, with subgenotype A1 being the most common. Finally, some studies discovered novel recombinant strains from HBV genotypes and subgenotypes. Conclusion: There were limited reports on HBV genotype across Africa, with scarce genotype and clinical linkages, making HBV genotype epidemiology a relevant gap for informed clinical decision-making in hepatitis B treatment.
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