Focal Signet Ring-Like Prostate Adenocarcinoma Detected on Microultrasound in the Setting of Negative Multiparametric Magnetic Resonance Imaging: A Case Report.

Kevin D Healey, James Blatchford, Shimron Brown, Emma Fenner, Phillip Latham, Nikhil Gopal

Abstract readCase Reports

In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Kevin D HealeyDepartment of Urology, The University of Tennessee Health Science Center, Memphis, USA.

James BlatchfordCollege of Medicine, The University of Tennessee Health Science Center, Memphis, USA.

Shimron BrownDepartment of Urology, The University of Tennessee Health Science Center, Memphis, USA.

Emma FennerDepartment of Urology, The University of Tennessee Health Science Center, Memphis, USA.

Phillip LathamDepartment of Urology, The University of Tennessee Health Science Center, Memphis, USA.

Nikhil GopalDepartment of Urology, The University of Tennessee Health Science Center, Memphis, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ExactVU microultrasound (microUS) (Exact Imaging, Markham, ON, Canada) is a novel imaging modality that incorporates a standardized lesion classification system known as Prostate Risk Identification using Micro-Ultrasound (PRIMUS) to detect prostate cancer lesions. Here, we report a case of a 65-year-old patient diagnosed with Gleason 5+4 acinar adenocarcinoma with focal signet ring-like (mucinous) features identified on microUS that was not visualized on multiparametric magnetic resonance imaging (mpMRI). This case highlights microUS as a promising tool to improve cancer detection when used in conjunction with mpMRI, as well as the need for further research regarding unconventional prostate cancer histologic variants.

Indexed as

androgen deprivation therapyprostate cancer radiation therapyprostate surgeryprostate tumorssignet ring cell adenocarcinoma

Identifiers

PMID42181497

DOI10.7759/cureus.107545

PMCPMC13197193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.