Evidence map›Paper›PMID 42181489›Full record

ArticleCureus2026

Severe Aortic and Mitral Regurgitation Secondary to Infective Endocarditis Presenting as Acute Respiratory Failure.

Mehul Mange, Deepak Sharma, Mahesh Eddula, Priyanka Sharma

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mehul MangeAnesthesia and Critical Care, Macclesfield District General Hospital, Macclesfield, GBR.
Deepak SharmaCritical Care Medicine, Sandwell and West Birmingham NHS Trust, Birmingham, GBR.
Mahesh EddulaAnesthesia and Critical Care, Macclesfield District General Hospital, Macclesfield, GBR.
Priyanka SharmaResearch and Development, University of Birmingham, Birmingham, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infective endocarditis (IE) typically presents with fever, a new or changing cardiac murmur, and embolic phenomena. Acute respiratory failure (ARF) as the dominant presenting feature, without overt cardiac signs, is uncommon and creates significant diagnostic challenges. We present a previously healthy 24-year-old man who attended the Emergency Department with fever, productive cough, and ARF requiring mechanical ventilation for bilateral pulmonary infiltrates. Cardiovascular examination on admission was unremarkable: there was no audible cardiac murmur and no peripheral stigmata of IE. Blood cultures subsequently yielded

Indexed as

acute respiratory failure (arf)infectious disease medicineinfective endocarditisinvasive mechanical ventilationvalvular-heart disease

Identifiers

PMID42181489
PMCPMC13198171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.