ArticleCureus2026
Emergence of Multidrug-Resistant Pathogens in a Tertiary Care Hospital in Northern India: A Comparative Study Between Critical Care Units and Wards.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim Multidrug-resistant organisms (MDROs) represent a major global public health concern, largely driven by inappropriate antibiotic use, over-the-counter availability of antimicrobials, and the absence of effective prescription audit systems. MDROs are microorganisms, most commonly bacteria, that exhibit resistance to one or more classes of antimicrobial agents. The burden of multidrug-resistant infections has increased worldwide, with marked rises in both healthcare-associated and community-acquired infections, particularly in regions with high levels of antibiotic misuse. This study aimed to characterize the spectrum of MDROs circulating in a tertiary care center, identify associated risk factors, and describe their antibiotic susceptibility patterns. Methods A prospective observational study was conducted over a period of one month, involving 1,223 clinical specimens from predefined areas. Specimens were processed for culture, identification, and antibiotic susceptibility testing. For all samples, patient demographic details, clinical information, and risk factors were documented and assessed. Infection prevention and control-related information was also documented. Data were analyzed using IBM SPSS Statistics for Windows, version 22.0 (released 2013; IBM Corp., Armonk, NY, USA), with the incorporation of the chi-square test for comparison between categorical variables, and a p-value of < 0.05 was considered statistically significant. Results Of the 1223 specimens, 1020 specimens were culture positive, with 240 (23.52%) yielding MDROs, with the highest proportions isolated from peritoneal fluid, CSF, and pus.
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