ArticleCureus2026
Prostate Cancer Presenting With Isolated Mediastinal Metastasis: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prostate cancer typically metastasizes in a predictable pattern, most commonly to the axial skeleton through Batson's venous plexus with associated regional pelvic lymphadenopathy. Mediastinal lymph node involvement is rare and represents an atypical route of dissemination that may lead to diagnostic uncertainty, particularly when thoracic findings predominate. We present a case of a 56-year-old Hispanic male with no significant past medical history with biopsy-confirmed prostatic adenocarcinoma with hematogenous mediastinal spread. CT imaging revealed extensive mediastinal, retroperitoneal, and pelvic lymphadenopathy with prostatic enlargement. This case highlights mediastinal lymph node metastasis as an uncommon initial manifestation of advanced prostate cancer and underscores the importance of tissue diagnosis in patients presenting with atypical thoracic adenopathy. Recognition of unusual metastatic patterns improves the understanding of tumor biology and may prevent misdiagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.