Evidence map›Paper›PMID 42181318›Full record

ArticleCureus2026

Toward the Abandonment of Axillary Surgery: Is This the End of an Era?

Maria Papadoliopoulou, Alexios Kozonis, Ioannis Margaris

Abstract readEditorial
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria Papadoliopoulou4th Department of Surgery, Attikon University Hospital, University of Athens, Athens, GRC.
Alexios KozonisDepartment of Obstetrics and Gynaecology, Attikon University Hospital, University of Athens, Athens, GRC.
Ioannis Margaris4th Department of Surgery, Attikon University Hospital, University of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Axillary surgery in breast cancer has evolved substantially from radical surgical approaches toward minimally invasive and, in selected cases, non-surgical strategies. This editorial summarizes emerging techniques for axillary staging, with particular emphasis on advanced imaging and optical spectroscopic methods, including contrast-enhanced ultrasonography, Raman spectroscopy, optical coherence tomography, Fourier-transform infrared spectroscopy, elastic scattering spectroscopy, and refractometry. These modalities demonstrate promising diagnostic accuracy and may allow for preoperative or intraoperative axillary staging, obviating the need for surgical excision. At the same time, ongoing randomized trials are investigating the omission of sentinel lymph node biopsy in carefully selected patients with early-stage breast cancer and clinically negative axillary lymph nodes. Early results suggest oncological safety in low-risk populations, although longer follow-up data are required. These developments suggest a future of personalized axillary management, potentially marking the beginning of the end for routine axillary surgery in breast cancer care.

Indexed as

axillary surgerybreast cancerimaging/spectroscopic techniquesomission of slnbsentinel lymph node biopsy (slnb)

Identifiers

PMID42181318
PMCPMC13197010

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.